Voyager I think was my favorite - only because the concept was way out there and the voyage back to earth could of made for many many more shows. ST:TNG did set the tone for what are todays younger trekkies, so it gets my second vote.
I was online the day that STO (Star Trek Online) was doing their presentation (and downloaded the vid afterwards), and I'm hoping they keep their word of sticking to as close to to the ST Universe as close as possible. I scan their boards a few times a week - but they are not NEARLY as organized as we are

so posts are lost too fast for me to keep up with topics (they really gotta fix that).