I agree with Ducky Wucky my favorite lines have to be:
(Scarlett and Giselle are fighting, Jack watches the Pearl sail away)
Jack Sparrow: "Ladies, will you please shut it! Listen to me.
(to Giselle)
Jack Sparrow: Yes, I lied to you.
(to Scarlett)
Jack Sparrow: No, I don't love you.
[to Giselle]
Jack Sparrow: Of course it makes you look fat.
(to Scarlett)
Jack Sparrow: I've never been to Brussels.
(to Giselle)
Jack Sparrow: It is pronounced *egregious*.
(to Scarlett)
Jack Sparrow: By the way, no. I've never actually met Pizarro, but I love his pies.
(to both)
Jack Sparrow: And all of this pales to utter insignificance in light of the fact that my ship is once again gone. Savvy?
(Giselle slaps him, Scarlett slaps him, he slaps Gibbs)"
Jack Sparrow: "And that was without even a single drop of rum. "
Jack Sparrow: "You may throw my hat if you wish.
(Gibbs throws Jack's hat)
Jack Sparrow: Now go and get it."