I have mastered 3 pirates so far and I am one level away from number four which I will do tonight as I type this.
I have been playing around seeing what happens when you make the wrong potion in bulk. Does it mess up the board? maybe a little,
You judge your self from this photo
on edit: I should add when this happens you get the bonus rep and all the chemicals used in the final concoction to get the bonus rep vanish and you continue making the rest of the actual potion or whatever. And like I said I did finish of the potions on number four pirate and I did this again and got a bonus over 400 but I was a bit slow on the screen capture.